122

Biochemistry

122.102 Biochemistry 15 credits
An introductory biochemistry course covering the fundamental concepts of protein structure and function as well as metabolism of carbohydrates, lipids and amino acids. The focus will be on energy transactions in a physiological context including glucose homeostasis and muscle metabolism in mammals. A lecture and problem-based tutorial course involving specific case studies will be complemented by a hands-on laboratory course.
122.106 Veterinary Biochemistry15 credits
An introductory biochemistry course covering the fundamental concepts of protein structure and function as well as metabolism of carbohydrates, lipids and amino acids. The focus will be on energy transactions in a physiological context including glucose homeostasis and muscle metabolism in mammals. A lecture and problem-based tutorial course will be complemented by case studies relevant to animal health and disease.
122.201 The Molecular Cell15 credits
Concepts of protein function, post-translational modification, folding, targeting and turn-over. The relationship between macromolecular structure/function and cell structure/function is explored with studies of cell membranes, the cell cytoskeletal, extracellular matrix and organelle organisation and function. Protein structure-function relationships will be discussed and analysed in the context of enzyme kinetics, enzyme catalysis and regulation.
122.202 The Dynamic Cell15 credits
Energy metabolism in higher eukaryotes from the perspective of life on earth and the necessary adaptation of living organisms from an anaerobic to aerobic environment. Carbohydrate, lipid and nitrogen metabolism in the context of health and disease. Integration and regulation of carbohydrate, lipid and amino acid metabolism. A lecture and problem-based tutorial course complemented by a hands-on project-based laboratory course.
122.222 Biochemistry for Technology15 credits
A foundation course that introduces molecular aspects of the cellular processes occurring in humans, animals, microbes and plants. An exploration of the molecules of life, proteins and enzymes in action, energy for living and energy storage with applications to the environment, health and disease, biotechnology, nutrition, sport and exercise. Theoretical aspects are supported by a laboratory programme focused on proteins and enzymes and their uses in diagnosing disease.
122.231 Genes and Gene Expression15 credits
Structure of DNA. Replication, DNA repair and transcription. Regulation of prokaryotic gene expression. Technologies used in the study of genes and gene expression: plasmids, sequencing, restriction enzymes, libraries, PCR, Southern, northern and western analysis, expression vectors and the production of recombinant proteins. A practical course that illustrates concepts presented in the lectures.
122.232 Protein Biochemistry15 credits
Protein biosynthesis, structure and function. Topics will include protein translation, folding, targeting and post-translational modification, the relationship between protein structure and function, enzyme kinetics, mechanisms of enzyme catalysis and control, membranes and membrane proteins. Lectures will be complemented with a practical course focused on developing the appropriate skills to investigate proteins.
122.233 Metabolic Biochemistry15 credits
Energy metabolism. Biosynthesis of carbohydrates and the metabolism of polysaccharides. Lipid metabolism. Nitrogen metabolism. Integration and regulation of carbohydrate, lipid and amino acid metabolism. Cellular communication systems.
122.301 Proteins and Cell Biology15 credits
The molecular mechanisms responsible for the signalling and biochemical responses of cells with a particular focus on protein structure and function. The course explores current methods of protein analysis, advanced studies in protein structure and function, cell signalling and cellular processes.
122.303 Gene Regulation15 credits
An advanced course on gene regulation. Topics include methods and experimental strategies for studying gene promoters and associated transcription factors, transcription initiation, transcription activation, role of chromatin structure in gene regulation, RNA processing, the role of non-coding RNA in gene expression and cytoplasmic control mechanisms.
122.322 Protein Structure and Function15 credits
The structural and biochemical basis of protein function will be explored with an emphasis on techniques of protein isolation and purification, current methods of protein analysis, enzyme function and kinetics, protein folding and molecular interactions. A laboratory and computer-based practical course in protein purification and analysis reinforces the theoretical aspects of the course.
122.703 Gene Expression30 credits
Advanced studies of selected topics in gene regulation at transcriptional and post-transcriptional levels.
122.704 Molecular Cell Biology30 credits
Advanced studies of selected topics in biochemistry and cell biology
122.713 Advanced Topics in Biochemistry15 credits
The course will involve use of the current literature to critically examine the experimental systems used to advance knowledge in Biochemistry.
122.798 Research Report30 credits
122.870 Research Report60 credits
122.871 Thesis 90 Credit Part 145 credits
A supervised and guided independent study resulting in a published work.
122.872 Thesis 90 Credit Part 245 credits
A supervised and guided independent study resulting in a published work
122.875 Thesis90 credits
A supervised and guided independent study resulting in a published work.
122.897 Thesis 120 Credit Part 160 credits
A supervised and guided independent study resulting in a published work.
122.898 Thesis 120 Credit Part 260 credits
A supervised and guided independent study resulting in a published work.
122.899 Thesis120 credits
A supervised and guided independent study resulting in a published work.
122.900 PhD Biochemistry120 credits

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